8SWI

Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide

Summary for 8SWI

• Entry DOI: 10.2210/pdb8swi/pdb
• Descriptor: Eukaryotic huntingtin interacting protein B, Histone H3 peptided, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: ankyrin repeats, histone methyltransferase activity, cell invasion
• Biological source: Legionella pneumophila subsp. pneumophila; More
• Total number of polymer chains: 2
• Total formula weight: 53610.17

Authors

Xu, C.,Chung, I.Y.W.,Cygler, M. (deposition date: 2023-05-18, release date: 2023-12-27)

• Primary citation: Rolando, M.,Wah Chung, I.Y.,Xu, C.,Gomez-Valero, L.,England, P.,Cygler, M.,Buchrieser, C.; The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.; Mbio, 14:e0165523-e0165523, 2023; PubMed: 37795993; DOI: 10.1128/mbio.01655-23

Experimental method

X-RAY DIFFRACTION (3 Å)