8SRK

Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose

Summary for 8SRK

• Entry DOI: 10.2210/pdb8srk/pdb
• EMDB information: 40734
• Descriptor: TRPM2 chanzyme, ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: trpm2 chanzyme, channel-enzyme, membrane protein
• Biological source: Salpingoeca rosetta
• Total number of polymer chains: 4
• Total formula weight: 556774.42

Authors

Huang, Y.,Kumar, S.,Lu, W.,Du, J. (deposition date: 2023-05-05, release date: 2024-05-15)

• Primary citation: Huang, Y.,Lu, W.,Du, J.; Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.14 Å)