8SO1

Human CYP3A4 bound to three caffeine molecules

Summary for 8SO1

Entry DOI	10.2210/pdb8so1/pdb
Descriptor	Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, CAFFEINE, ... (4 entities in total)
Functional Keywords	substrate, complex, oxidoreductase, oxidoreductase-substrate complex, oxidoreductase/substrate
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	56956.87
Authors	Sevrioukova, I.F. (deposition date: 2023-04-28, release date: 2023-08-02, Last modification date: 2023-09-06)
Primary citation	Sevrioukova, I.F. Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. J.Biol.Chem., 299:105117-105117, 2023 Cited by PubMed: 37524132 DOI: 10.1016/j.jbc.2023.105117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation