8SIM

KCNQ1 with voltage sensor in the intermediate conformation

Summary for 8SIM

Entry DOI	10.2210/pdb8sim/pdb
EMDB information	40509
Descriptor	Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1, CALCIUM ION (3 entities in total)
Functional Keywords	voltage-gated potassium channel, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	320765.10
Authors	Mandala, V.S.,MacKinnon, R. (deposition date: 2023-04-16, release date: 2023-05-31)
Primary citation	Mandala, V.S.,MacKinnon, R. The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel. Proc.Natl.Acad.Sci.USA, 120:e2301985120-e2301985120, 2023 Cited by PubMed: 37192161 DOI: 10.1073/pnas.2301985120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.2 Å)

Structure validation