8SCK

Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h

Summary for 8SCK

• Entry DOI: 10.2210/pdb8sck/pdb
• Descriptor: DNA polymerase I, DNA primer/product, DNA template, ... (8 entities in total)
• Functional Keywords: dna polymerase, np-dna, origin of life, time-resolved crystallography, dna binding protein, replication-dna complex, replication/dna
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 6
• Total formula weight: 147985.37

Authors

Fang, Z.,Lelyveld, V.S.,Szostak, J.W. (deposition date: 2023-04-05, release date: 2023-10-25, Last modification date: 2023-11-08)

• Primary citation: Lelyveld, V.S.,Fang, Z.,Szostak, J.W.; Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.; Science, 382:423-429, 2023; PubMed: 37883544; DOI: 10.1126/science.adh5339

Experimental method

X-RAY DIFFRACTION (2.3 Å)