8SBD
Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments
Summary for 8SBD
| Entry DOI | 10.2210/pdb8sbd/pdb |
| EMDB information | 40305 |
| Descriptor | Insulin B chain, Insulin A chain (2 entities in total) |
| Functional Keywords | amyloid-like fibril, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 32 |
| Total formula weight | 93082.42 |
| Authors | Wang, L.W.,Hall, C.,Uchikawa, E.,Chen, D.L.,Choi, E.,Zhang, X.W.,Bai, X.C. (deposition date: 2023-04-03, release date: 2023-08-30, Last modification date: 2023-09-27) |
| Primary citation | Wang, L.,Hall, C.E.,Uchikawa, E.,Chen, D.,Choi, E.,Zhang, X.,Bai, X.C. Structural basis of insulin fibrillation. Sci Adv, 9:eadi1057-eadi1057, 2023 Cited by PubMed: 37713485DOI: 10.1126/sciadv.adi1057 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
Download full validation report
