8RM7

Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: MMTV-177 GRE/ARE

Summary for 8RM7

Entry DOI	10.2210/pdb8rm7/pdb
Descriptor	Isoform 2 of Androgen receptor, MMTV-177 GRE/ARE Chain C, MMTV-177 GRE/ARE, Chain D, ... (5 entities in total)
Functional Keywords	dbd-dna binding complex, androgen receptor dna binding domain, structural protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	27379.67
Authors	Lee, X.Y.,Helsen, C.,Van Eynde, W.,Voet, A.,Claessens, F. (deposition date: 2024-01-05, release date: 2024-04-24)
Primary citation	Lee, X.Y.,Van Eynde, W.,Helsen, C.,Willems, H.,Peperstraete, K.,De Block, S.,Voet, A.,Claessens, F. Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241:106499-106499, 2024 Cited by PubMed: 38604378 DOI: 10.1016/j.jsbmb.2024.106499 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation