8R5C
Crystal structure of human TRIM7 PRYSPRY domain bound to (2-(1-oxoisoindolin-2-yl)-3-phenylpropanoyl)-L-glutamine
Summary for 8R5C
Entry DOI | 10.2210/pdb8r5c/pdb |
Descriptor | E3 ubiquitin-protein ligase TRIM7, (2~{S})-5-azanyl-5-oxidanylidene-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]pentanoic acid, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | trim7, e3-ligase, ligand, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 20642.16 |
Authors | Munoz Sosa, C.J.,Kraemer, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-11-16, release date: 2024-01-17) |
Primary citation | Munoz Sosa, C.J.,Kraemer, A.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of human TRIM7 PRYSPRY domain To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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