8R1V

Pseudomonas aeruginosa FabF C164A in complex with N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(4-methoxyphenoxy)acetamide

Summary for 8R1V

• Entry DOI: 10.2210/pdb8r1v/pdb
• Related: 8R0I
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(4-methoxyphenoxy)acetamide, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: inhibitor, protein-ligand complex, fabf, transferase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 89206.23

Authors

Yadrykhinsky, V.,Brenk, R. (deposition date: 2023-11-02, release date: 2024-03-06)

• Primary citation: Jalencas, X.,Berg, H.,Espeland, L.O.,Sreeramulu, S.,Kinnen, F.,Richter, C.,Georgiou, C.,Yadrykhinsky, V.,Specker, E.,Jaudzems, K.,Miletic, T.,Harmel, R.,Gribbon, P.,Schwalbe, H.,Brenk, R.,Jirgensons, A.,Zaliani, A.,Mestres, J.; Design, Quality and Validation of the EU-OPENSCREEN Fragment Library Poised to a High-Throughput Screening Collection; Rsc Med Chem, 2024; DOI: 10.1039/D3MD00724C

Experimental method

X-RAY DIFFRACTION (2.087 Å)