8QYF

Crystal structure of ClpP from Staphylococcus epidermidis in complex with ixazomib

Summary for 8QYF

Entry DOI	10.2210/pdb8qyf/pdb
Descriptor	ATP-dependent Clp protease proteolytic subunit, [(1~{R})-1-[2-[[2,5-bis(chloranyl)phenyl]carbonylamino]ethanoylamino]-3-methyl-butyl]boronic acid (3 entities in total)
Functional Keywords	clpp, serine protease, complex, hydrolase
Biological source	Staphylococcus epidermidis
Total number of polymer chains	14
Total formula weight	316347.28
Authors	Franca, B.A.,Rohde, H.,Betzel, C. (deposition date: 2023-10-26, release date: 2024-01-17, Last modification date: 2024-02-14)
Primary citation	Alves Franca, B.,Falke, S.,Rohde, H.,Betzel, C. Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds. Sci Rep, 14:2572-2572, 2024 Cited by PubMed: 38296985 DOI: 10.1038/s41598-024-51787-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation