8QYA

J22.9-FNY, fully humanized, CDR optimized Fab Fragment based on chimeric J22.9-xi IgG against BCMA; with VH CDR2 glycosylation

Summary for 8QYA

• Entry DOI: 10.2210/pdb8qya/pdb
• Descriptor: Chains: L, Chains: H, Chains: A, ... (6 entities in total)
• Functional Keywords: fab fragment, humanized, cdr derivatized, bcma binding, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 50628.31

Authors

Marino, S.F.,Daumke, O. (deposition date: 2023-10-25, release date: 2024-01-17)

• Primary citation: Marino, S.F.,Daumke, O.; Structure-based humanization of a therapeutic antibody for Multiple Myeloma; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.72 Å)