8QQ7

Structure of SpNOX: a Bacterial NADPH oxidase

Summary for 8QQ7

Entry DOI	10.2210/pdb8qq7/pdb
Descriptor	FAD-binding FR-type domain-containing protein, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	nadph oxidase, reactive oxygen species production, membrane protein, streptococcus pneumoniae, f397w mutant, electron transport., electron transport
Biological source	Streptococcus pneumoniae
Total number of polymer chains	1
Total formula weight	48251.32
Authors	Thepaut, M.,Petit-Hartlein, I.,Vermot, A.,Chaptal, V.,Humm, A.S.,Dupeux, F.,Marquez, J.A.,Smith, S.,Fieschi, F. (deposition date: 2023-10-04, release date: 2024-05-08)
Primary citation	Petit-Hartlein, I.,Vermot, A.,Thepaut, M.,Humm, A.S.,Dupeux, F.,Dupuy, J.,Chaptal, V.,Marquez, J.A.,Smith, S.M.E.,Fieschi, F. X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX. Elife, 13:-, 2024 Cited by PubMed: 38640072 DOI: 10.7554/eLife.93759 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.62 Å)

Structure validation