8Q6O

X. laevis CMG dimer bound to dimeric DONSON - without ATPase

Summary for 8Q6O

Entry DOI	10.2210/pdb8q6o/pdb
EMDB information	18191
Descriptor	DNA replication licensing factor mcm2, Cell division control protein 45 homolog, DNA replication complex GINS protein SLD5, ... (13 entities in total)
Functional Keywords	dna replication initiation, xenopus egg extract, primordial dwarfism, replicative helicase, genome stability, replication
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	24
Total formula weight	1538548.24
Authors	Butryn, A.,Cvetkovic, M.A.,Costa, A. (deposition date: 2023-08-14, release date: 2023-10-18, Last modification date: 2023-11-29)
Primary citation	Cvetkovic, M.A.,Passaretti, P.,Butryn, A.,Reynolds-Winczura, A.,Kingsley, G.,Skagia, A.,Fernandez-Cuesta, C.,Poovathumkadavil, D.,George, R.,Chauhan, A.S.,Jhujh, S.S.,Stewart, G.S.,Gambus, A.,Costa, A. The structural mechanism of dimeric DONSON in replicative helicase activation. Mol.Cell, 83:4017-, 2023 Cited by PubMed: 37820732 DOI: 10.1016/j.molcel.2023.09.029 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.14 Å)

Structure validation