8PYR

Crystal structure of the dual T-loop phosphorylated Cdk7/CycH/Mat1 complex

Summary for 8PYR

• Entry DOI: 10.2210/pdb8pyr/pdb
• Descriptor: Cyclin-dependent kinase 7, Cyclin-H, CDK-activating kinase assembly factor MAT1, ... (6 entities in total)
• Functional Keywords: cdk7, cyclin h, mat1, cdk activating kinase, kinase, phosphorylation, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 197237.91

Authors

Anand, K.,Duster, R.,Geyer, M. (deposition date: 2023-07-26, release date: 2024-03-06)

• Primary citation: Duster, R.,Anand, K.,Binder, S.C.,Schmitz, M.,Gatterdam, K.,Fisher, R.P.,Geyer, M.; Structural basis of Cdk7 activation by dual T-loop phosphorylation.; Biorxiv, 2024; PubMed: 38405971; DOI: 10.1101/2024.02.14.580246

Experimental method

X-RAY DIFFRACTION (2.15 Å)