8P6Q

Racemic structure of TNFR1 cysteine-rich domain

Summary for 8P6Q

• Entry DOI: 10.2210/pdb8p6q/pdb
• Descriptor: Tumor necrosis factor-binding protein 1, D-TNFR-1 CRD2, SULFATE ION, ... (4 entities in total)
• Functional Keywords: racemic, chemical synthesis, cysteine-rich, cytokine receptor, receptor mimic, cytokine
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 11559.65

Authors

Lander, A.J.,Jin, Y.,Luk, L.Y.P. (deposition date: 2023-05-28, release date: 2024-01-24, Last modification date: 2024-03-06)

• Primary citation: Lander, A.J.,Kong, Y.,Jin, Y.,Wu, C.,Luk, L.Y.P.; Deciphering the Synthetic and Refolding Strategy of a Cysteine-Rich Domain in the Tumor Necrosis Factor Receptor (TNF-R) for Racemic Crystallography Analysis and d-Peptide Ligand Discovery.; Acs Bio Med Chem Au, 4:68-76, 2024; PubMed: 38404743; DOI: 10.1021/acsbiomedchemau.3c00060

Experimental method

X-RAY DIFFRACTION (1.4 Å)