8ORC

Mus Musculus Acetylcholinesterase in complex with AL237

Summary for 8ORC

• Entry DOI: 10.2210/pdb8orc/pdb
• Descriptor: Acetylcholinesterase, 1-[2-(dimethylamino)ethyl]-3-(2-methoxyphenyl)thiourea, 2-(2-METHOXYETHOXY)ETHANOL, ... (7 entities in total)
• Functional Keywords: neurotransmission, cholinesterase, inhibitor, hydrolase
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 2
• Total formula weight: 121609.62

Authors

Ekstrom, F.E.,Linusson, A. (deposition date: 2023-04-13, release date: 2024-04-24)

• Primary citation: Kumari, R.,Lindgren, C.,Kumar, R.,Forsgren, N.,Andersson, D.,Ekstrom, F.,Linusson, A.; Enzyme Dynamics Determine Potency and Selectivity of Inhibitors Targeting Disease-Transmitting Mosquitoes; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)