8OQ5

AApoAII amyloid fibril Morphology I (ex vivo)

Summary for 8OQ5

Entry DOI	10.2210/pdb8oq5/pdb
EMDB information	17105
Descriptor	Apolipoprotein A-II (1 entity in total)
Functional Keywords	amyloid, protein fibril, systemic amyloidosis, misfolding disease, helical
Biological source	Mus musculus (house mouse)
Total number of polymer chains	12
Total formula weight	104960.74
Authors	Andreotti, G.,Schmidt, M.,Faendrich, M. (deposition date: 2023-04-11, release date: 2024-02-21)
Primary citation	Andreotti, G.,Baur, J.,Ugrina, M.,Pfeiffer, P.B.,Hartmann, M.,Wiese, S.,Miyahara, H.,Higuchi, K.,Schwierz, N.,Schmidt, M.,Fandrich, M. Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils. J.Mol.Biol., 436:168441-168441, 2024 Cited by PubMed: 38199491 DOI: 10.1016/j.jmb.2024.168441 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.4 Å)

Structure validation