8OHA

Crystal structure of Leptospira interrogans GAPDH

Summary for 8OHA

• Entry DOI: 10.2210/pdb8oha/pdb
• Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... (7 entities in total)
• Functional Keywords: gapdh, leptospira interrogans, immune evasion, innate immunity, complement system, hydrolase
• Biological source: Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130; More
• Total number of polymer chains: 8
• Total formula weight: 304279.44

Authors

Navas-Yuste, S.,de la Paz, K.,Querol-Garcia, J.,Gomez-Quevedo, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. (deposition date: 2023-03-20, release date: 2023-08-23)

• Primary citation: Navas-Yuste, S.,de la Paz, K.,Querol-Garcia, J.,Gomez-Quevedo, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C.; The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity.; Front Immunol, 14:1190943-1190943, 2023; PubMed: 37409124; DOI: 10.3389/fimmu.2023.1190943

Experimental method

X-RAY DIFFRACTION (2.37 Å)