8OH8
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group P 21 21 21)
This is a non-PDB format compatible entry.
Summary for 8OH8
| Entry DOI | 10.2210/pdb8oh8/pdb |
| Descriptor | Uricase, 8-AZAXANTHINE, 1,2-ETHANEDIOL, ... (7 entities in total) |
| Functional Keywords | cofactor-free oxidase, inhibitor, dioxygen binding, cysteine, oxidoreductase |
| Biological source | Gallus gallus (chicken) |
| Total number of polymer chains | 4 |
| Total formula weight | 158914.59 |
| Authors | Di Palma, M.,Chegkazi, M.,Bui, S.,Mori, G.,Percudani, R.,Steiner, R.A. (deposition date: 2023-03-20, release date: 2024-01-17) |
| Primary citation | Mori, G.,Liuzzi, A.,Ronda, L.,Di Palma, M.,Chegkazi, M.S.,Bui, S.,Garcia-Maya, M.,Ragazzini, J.,Malatesta, M.,Della Monica, E.,Rivetti, C.,Antin, P.B.,Bettati, S.,Steiner, R.A.,Percudani, R. Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism. Mol.Biol.Evol., 40:-, 2023 Cited by PubMed: 37695804DOI: 10.1093/molbev/msad200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
Download full validation report
