8JYW

Cryo-EM structure of the gasdermin pore from Trichoplax adhaerens

This is a non-PDB format compatible entry.

Summary for 8JYW

• Entry DOI: 10.2210/pdb8jyw/pdb
• EMDB information: 36732
• Descriptor: Gasdermin pore forming domain-containing protein (1 entity in total)
• Functional Keywords: pyroptosis, ggasdermin, pore-forming, immune system
• Biological source: Trichoplax adhaerens
• Total number of polymer chains: 88
• Total formula weight: 2394775.24

Authors

Hou, Y.J.,Sun, Q.,Zeng, H.,Ding, J. (deposition date: 2023-07-04, release date: 2024-05-01, Last modification date: 2024-05-15)

• Primary citation: Li, Y.,Hou, Y.,Sun, Q.,Zeng, H.,Meng, F.,Tian, X.,He, Q.,Shao, F.,Ding, J.; Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.; Science, :eadm9190-eadm9190, 2024; PubMed: 38662913; DOI: 10.1126/science.adm9190

Experimental method

ELECTRON MICROSCOPY (3.3 Å)