8JTD

BJOX2000.664 trimer in complex with Fab fragment of broadly neutralizing HIV antibody PGT145

Summary for 8JTD

• Entry DOI: 10.2210/pdb8jtd/pdb
• EMDB information: 36630 36641
• Descriptor: gp120 protein of HIV Envelope trimer, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: hiv, envelope trimer, broadly neutralizing antibody, pgt145, cryo-em, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 8
• Total formula weight: 292018.97

Authors

Chatterjee, A.,Chen, C.,Lee, K.,Mangala Prasad, V. (deposition date: 2023-06-21, release date: 2023-10-25)

• Primary citation: Hodge, E.A.,Chatterjee, A.,Chen, C.,Naika, G.S.,Laohajaratsang, M.,Mangala Prasad, V.,Lee, K.K.; An HIV-1 broadly neutralizing antibody overcomes structural and dynamic variation through highly focused epitope targeting.; Npj Viruses, 1:-, 2023; DOI: 10.1038/s44298-023-00002-4

Experimental method

ELECTRON MICROSCOPY (4.9 Å)