8JFV

Crystal structure of Catabolite repressor acivator from E. coli in complex with sulisobenzone

Summary for 8JFV

Entry DOI	10.2210/pdb8jfv/pdb
Descriptor	Catabolite repressor/activator, 2-methoxy-4-oxidanyl-5-(phenylcarbonyl)benzenesulfonic acid, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	transcription factor, bacterial, sulsiobenzone, transcription
Biological source	Escherichia coli 536
Total number of polymer chains	2
Total formula weight	76806.31
Authors	Neetu, N.,Sharma, M.,Mahto, J.K.,Kumar, P. (deposition date: 2023-05-19, release date: 2024-04-24)
Primary citation	Neetu, N.,Mahto, J.K.,Sharma, M.,Katiki, M.,Dhaka, P.,Roy, P.,Tomar, S.,Narayan, A.,Yernool, D.,Kumar, P. Sulisobenzone is a potent inhibitor of the global transcription factor Cra. J.Struct.Biol., 215:108034-108034, 2023 Cited by PubMed: 37805153 DOI: 10.1016/j.jsb.2023.108034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation