8IQ9

Crystal structure of trimeric K2-2 TSP in complex with tetrasaccharide and octasaccharide

Summary for 8IQ9

• Entry DOI: 10.2210/pdb8iq9/pdb
• Descriptor: K2-2 TSP, alpha-D-glucopyranuronic acid-(1-3)-beta-D-mannopyranose-(1-4)-alpha-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-[alpha-D-glucopyranuronic acid-(1-3)]beta-D-mannopyranose-(1-4)-alpha-D-glucopyranose-(1-3)-beta-D-glucopyranose, alpha-D-glucopyranuronic acid-(1-3)-beta-D-mannopyranose-(1-4)-alpha-D-glucopyranose-(1-3)-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: bacteriophage, tailspike protein, klebsiella pneumoniae k2, hydrolase
• Biological source: Klebsiella phage VLC6
• Total number of polymer chains: 3
• Total formula weight: 200376.29

Authors

Ye, T.J.,Ko, T.P.,Huang, K.F.,Wu, S.H. (deposition date: 2023-03-16, release date: 2024-02-21, Last modification date: 2024-04-03)

• Primary citation: Ye, T.J.,Fung, K.M.,Lee, I.M.,Ko, T.P.,Lin, C.Y.,Wong, C.L.,Tu, I.F.,Huang, T.Y.,Yang, F.L.,Chang, Y.P.,Wang, J.T.,Lin, T.L.,Huang, K.F.,Wu, S.H.; Klebsiella pneumoniae K2 capsular polysaccharide degradation by a bacteriophage depolymerase does not require trimer formation.; Mbio, 15:e0351923-e0351923, 2024; PubMed: 38349137; DOI: 10.1128/mbio.03519-23

Experimental method

X-RAY DIFFRACTION (1.58 Å)