8IHO

Crystal structures of SARS-CoV-2 papain-like protease in complex with covalent inhibitors

Summary for 8IHO

Entry DOI	10.2210/pdb8iho/pdb
Descriptor	Papain-like protease nsp3, covalent inhibitor, ZINC ION (3 entities in total)
Functional Keywords	viral protein-inhibitor complex, viral protein/inhibitor
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	4
Total formula weight	72729.41
Authors	Wang, Q.,Hu, H.,Li, M.,Xu, Y. (deposition date: 2023-02-23, release date: 2024-01-03)
Primary citation	Wang, Q.,Chen, G.,He, J.,Li, J.,Xiong, M.,Su, H.,Li, M.,Hu, H.,Xu, Y. Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 37239980 DOI: 10.3390/ijms24108633 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation