8HZR

Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332

Summary for 8HZR

• Entry DOI: 10.2210/pdb8hzr/pdb
• Descriptor: 3C-like proteinase nsp5, (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 66784.24

Authors

Zeng, X.Y.,Zhang, J.,Li, J. (deposition date: 2023-01-09, release date: 2024-01-17)

• Primary citation: Zeng, X.Y.,Zhang, J.,Li, J.; Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)