8HRX

Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex

Summary for 8HRX

Entry DOI	10.2210/pdb8hrx/pdb
EMDB information	34981
Descriptor	Sodium/bile acid cotransporter, PreS1 protein (Fragment), Fab heavy chain from antibody IgG clone number YN9048, ... (4 entities in total)
Functional Keywords	hepatitis, hbv, transport protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	94670.33
Authors	Asami, J.,Shimizu, T.,Ohto, U. (deposition date: 2022-12-16, release date: 2024-01-17, Last modification date: 2024-04-03)
Primary citation	Asami, J.,Park, J.H.,Nomura, Y.,Kobayashi, C.,Mifune, J.,Ishimoto, N.,Uemura, T.,Liu, K.,Sato, Y.,Zhang, Z.,Muramatsu, M.,Wakita, T.,Drew, D.,Iwata, S.,Shimizu, T.,Watashi, K.,Park, S.Y.,Nomura, N.,Ohto, U. Structural basis of hepatitis B virus receptor binding. Nat.Struct.Mol.Biol., 31:447-454, 2024 Cited by PubMed: 38233573 DOI: 10.1038/s41594-023-01191-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.89 Å)

Structure validation