8HNC

Cryo-EM structure of human OATP1B1 in complex with bilirubin

Summary for 8HNC

• Entry DOI: 10.2210/pdb8hnc/pdb
• EMDB information: 34910
• Descriptor: Solute carrier organic anion transporter family member 1B1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ... (4 entities in total)
• Functional Keywords: transporter, oatp1b1, organic anion transporting peptide, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 80021.02

Authors

Shan, Z.,Yang, X.,Liu, H.,Nan, J.,Yuan, Y.,Zhang, Y. (deposition date: 2022-12-07, release date: 2023-09-13, Last modification date: 2023-12-20)

• Primary citation: Shan, Z.,Yang, X.,Liu, H.,Yuan, Y.,Xiao, Y.,Nan, J.,Zhang, W.,Song, W.,Wang, J.,Wei, F.,Zhang, Y.; Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.; Cell Res., 33:940-951, 2023; PubMed: 37674011; DOI: 10.1038/s41422-023-00870-8

Experimental method

ELECTRON MICROSCOPY (3.73 Å)