8HLQ

Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827)

Summary for 8HLQ

• Entry DOI: 10.2210/pdb8hlq/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, GLYCEROL, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, ... (4 entities in total)
• Functional Keywords: dna adp-ribosyltransferase 2, parp2, niraparib, mk-4827, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 80848.88

Authors

Wang, X.Y.,Zhou, J.,Xu, B.L. (deposition date: 2022-11-30, release date: 2024-05-01)

• Primary citation: Wang, X.Y.,Zhou, J.,Xu, B.L.; Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)