8HLJ

Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281)

Summary for 8HLJ

• Entry DOI: 10.2210/pdb8hlj/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one (3 entities in total)
• Functional Keywords: dna adp-ribosyltransferase 2, parp2, olaparib, azd2281, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 80800.75

Authors

Wang, X.Y.,Zhou, J.,Xu, B.L. (deposition date: 2022-11-30, release date: 2024-05-01)

• Primary citation: Wang, X.Y.,Zhou, J.,Xu, B.L.; Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.24 Å)