8H3S

Substrate-bound EP, polyA model

Summary for 8H3S

• Entry DOI: 10.2210/pdb8h3s/pdb
• EMDB information: 32829
• Descriptor: Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain, Serine protease 1 (3 entities in total)
• Functional Keywords: complex, membrane protein, membrane protein-hydrolase complex, membrane protein/hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 117845.63

Authors

Ding, Z.Y.,Huang, H.J. (deposition date: 2022-10-09, release date: 2022-11-23)

• Primary citation: Yang, X.,Ding, Z.,Peng, L.,Song, Q.,Zhang, D.,Cui, F.,Xia, C.,Li, K.,Yin, H.,Li, S.,Li, Z.,Huang, H.; Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase.; Nat Commun, 13:6955-6955, 2022; PubMed: 36376282; DOI: 10.1038/s41467-022-34364-9

Experimental method

ELECTRON MICROSCOPY (4.9 Å)