8G94
Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi
Summary for 8G94
Entry DOI | 10.2210/pdb8g94/pdb |
EMDB information | 29861 |
Descriptor | Sphingosine 1-phosphate receptor 1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | cd69, s1pr1, sphingosine-1-phosphate, lymphocyte egress, gpcr, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 201728.62 |
Authors | |
Primary citation | Chen, H.,Qin, Y.,Chou, M.,Cyster, J.G.,Li, X. Transmembrane protein CD69 acts as an S1PR1 agonist. Elife, 12:-, 2023 Cited by PubMed: 37039481DOI: 10.7554/eLife.88204 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.15 Å) |
Structure validation
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