8G25
Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 7.5
Summary for 8G25
Entry DOI | 10.2210/pdb8g25/pdb |
Descriptor | Cathepsin-G, Neutrophil elastase, MAP domain-containing protein, ... (4 entities in total) |
Functional Keywords | protease inhibitor, immune evasion, neutrophil, s. aureus, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Staphylococcus aureus subsp. aureus Mu50 More |
Total number of polymer chains | 9 |
Total formula weight | 185520.08 |
Authors | Mishra, N.B.,Geisbrecht, B.V. (deposition date: 2023-02-03, release date: 2023-04-26, Last modification date: 2023-10-25) |
Primary citation | Mishra, N.,Herdendorf, T.J.,Prakash, O.,Geisbrecht, B.V. Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2. J.Biol.Chem., 299:104878-104878, 2023 Cited by PubMed: 37269950DOI: 10.1016/j.jbc.2023.104878 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png)