8FRG

Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH 5.43

Summary for 8FRG

• Entry DOI: 10.2210/pdb8frg/pdb
• Descriptor: Acidic mammalian chitinase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: gh18 chitinase, acidic mammalian chitinase, hydrolase
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 2
• Total formula weight: 90990.20

Authors

Diaz, R.E.,Fraser, J.S. (deposition date: 2023-01-06, release date: 2023-03-15, Last modification date: 2024-04-10)

• Primary citation: Diaz, R.E.,Ecker, A.K.,Correy, G.J.,Asthana, P.,Young, I.D.,Faust, B.,Thompson, M.C.,Seiple, I.B.,Van Dyken, S.J.,Locksley, R.M.,Fraser, J.S.; Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.; Biorxiv, 2024; PubMed: 37398339; DOI: 10.1101/2023.06.03.542675

Experimental method

X-RAY DIFFRACTION (1.74 Å)