8FMG

Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (3 tetramers in the AU)

Summary for 8FMG

Entry DOI	10.2210/pdb8fmg/pdb
Descriptor	SAVED domain-containing protein, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	cyclic dinucleotide, bacterial immunity, cbass, cap5 effector dna endonuclease, viral defense, immune system
Biological source	Pseudomonas syringae
Total number of polymer chains	12
Total formula weight	522232.67
Authors	Rechkoblit, O.,Kreitler, D.F.,Aggarwal, A.K. (deposition date: 2022-12-23, release date: 2024-02-07, Last modification date: 2024-02-21)
Primary citation	Rechkoblit, O.,Sciaky, D.,Kreitler, D.F.,Buku, A.,Kottur, J.,Aggarwal, A.K. Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38321146 DOI: 10.1038/s41594-024-01220-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation