8FG1

Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain

Summary for 8FG1

• Entry DOI: 10.2210/pdb8fg1/pdb
• NMR Information: BMRB: 31064
• Descriptor: Protein diaphanous homolog 1 (2 entities in total)
• Functional Keywords: inhibitory domain, autoregulatory domain, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 32277.92

Authors

Ramirez, L.M.S.,Theophall, G.,Premo, A.,Manigrasso, M.,Yepuri, G.,Burz, D.,Ramasamy, R.,Schmidt, A.M.,Shekhtman, A. (deposition date: 2022-12-12, release date: 2023-10-25, Last modification date: 2023-11-15)

• Primary citation: Theophall, G.G.,Ramirez, L.M.S.,Premo, A.,Reverdatto, S.,Manigrasso, M.B.,Yepuri, G.,Burz, D.S.,Ramasamy, R.,Schmidt, A.M.,Shekhtman, A.; Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity.; J.Biol.Chem., 299:105342-105342, 2023; PubMed: 37832872; DOI: 10.1016/j.jbc.2023.105342

Experimental method

SOLUTION NMR