8FFO

Cryo-EM structure of wildtype rabbit TRPV5 with PI(4,5)P2 in nanodiscs

Summary for 8FFO

Entry DOI	10.2210/pdb8ffo/pdb
EMDB information	29049
Descriptor	Transient receptor potential cation channel subfamily V member 5, ERGOSTEROL, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (4 entities in total)
Functional Keywords	trpv5, trp channel, pi(4, 5)p2, membrane protein
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	4
Total formula weight	353426.75
Authors	De Jesus-Perez, J.J.,Moiseenkova-Bell, V.Y. (deposition date: 2022-12-09, release date: 2023-11-01)
Primary citation	Lee, B.H.,De Jesus Perez, J.J.,Moiseenkova-Bell, V.,Rohacs, T. Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nat Commun, 14:5883-5883, 2023 Cited by PubMed: 37735536 DOI: 10.1038/s41467-023-41577-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation