8FDC

Crystal structure of Ky311 Fab in complex with circumsporozoite protein KQPA peptide

Summary for 8FDC

• Entry DOI: 10.2210/pdb8fdc/pdb
• Descriptor: Circumsporozoite protein KQPA peptide, Ky311 Antibody, heavy chain, Ky311 Antibody, light chain, ... (5 entities in total)
• Functional Keywords: malaria, antibody, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 49424.03

Authors

Burn Aschner, C.,Julien, J.P. (deposition date: 2022-12-02, release date: 2023-11-01, Last modification date: 2024-03-20)

• Primary citation: Thai, E.,Murugan, R.,Binter, S.,Burn Aschner, C.,Prieto, K.,Kassardjian, A.,Obraztsova, A.S.,Kang, R.W.,Flores-Garcia, Y.,Mathis-Torres, S.,Li, K.,Horn, G.Q.,Huntwork, R.H.C.,Bolscher, J.M.,de Bruijni, M.H.C.,Sauerwein, R.,Dennison, S.M.,Tomaras, G.D.,Zavala, F.,Kellam, P.,Wardemann, H.,Julien, J.P.; Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.; Cell Rep, 42:113330-113330, 2023; PubMed: 38007690; DOI: 10.1016/j.celrep.2023.113330

Experimental method

X-RAY DIFFRACTION (1.8 Å)