8FA9

Crystal structure of Ky15.5 Fab in complex with circumsporozoite protein NPDP peptide

Summary for 8FA9

Entry DOI	10.2210/pdb8fa9/pdb
Descriptor	Ky15.5 Antibody, heavy chain, Ky15.5 Antibody, light chain, Circumsporozoite protein NPDP peptide, ... (4 entities in total)
Functional Keywords	malaria, antibody, immune system
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	3
Total formula weight	49605.19
Authors	Thai, E.,Prieto, K.,Julien, J.P. (deposition date: 2022-11-25, release date: 2023-11-01, Last modification date: 2024-03-20)
Primary citation	Thai, E.,Murugan, R.,Binter, S.,Burn Aschner, C.,Prieto, K.,Kassardjian, A.,Obraztsova, A.S.,Kang, R.W.,Flores-Garcia, Y.,Mathis-Torres, S.,Li, K.,Horn, G.Q.,Huntwork, R.H.C.,Bolscher, J.M.,de Bruijni, M.H.C.,Sauerwein, R.,Dennison, S.M.,Tomaras, G.D.,Zavala, F.,Kellam, P.,Wardemann, H.,Julien, J.P. Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42:113330-113330, 2023 Cited by PubMed: 38007690 DOI: 10.1016/j.celrep.2023.113330 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation