8F2P

Nef SF2 dimerization mutant bound to Hck SH3

Summary for 8F2P

Entry DOI	10.2210/pdb8f2p/pdb
Descriptor	C-terminal core protein, Tyrosine-protein kinase HCK (3 entities in total)
Functional Keywords	protein complex, nef, hck, sh3, viral protein
Biological source	HIV-1 M:B_ARV2/SF2 More
Total number of polymer chains	2
Total formula weight	26150.32
Authors	Thomas, C.E.,Alvarado, J.J.,Smithgall, T.E. (deposition date: 2022-11-08, release date: 2023-02-22, Last modification date: 2023-10-25)
Primary citation	Heinrich, F.,Thomas, C.E.,Alvarado, J.J.,Eells, R.,Thomas, A.,Doucet, M.,Whitlatch, K.N.,Aryal, M.,Losche, M.,Smithgall, T.E. Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers. J.Mol.Biol., 435:168009-168009, 2023 Cited by PubMed: 36773691 DOI: 10.1016/j.jmb.2023.168009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation