8ETP

Cryo-EM structure of cGMP bound closed state of human CNGA3/CNGB3 channel in GDN

Summary for 8ETP

• Entry DOI: 10.2210/pdb8etp/pdb
• EMDB information: 28595
• Descriptor: Cyclic nucleotide-gated cation channel alpha-3, Cyclic nucleotide-gated cation channel beta-3, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: heterotetramer, ligand-bound, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 331147.73

Authors

Hu, Z.,Zheng, X.,Yang, J. (deposition date: 2022-10-17, release date: 2023-08-02)

• Primary citation: Hu, Z.,Zheng, X.,Yang, J.; Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.; Nat Commun, 14:4284-4284, 2023; PubMed: 37463923; DOI: 10.1038/s41467-023-39971-8

Experimental method

ELECTRON MICROSCOPY (3.52 Å)