8EQI
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with cyclopeptide des4.2.0
Summary for 8EQI
| Entry DOI | 10.2210/pdb8eqi/pdb |
| Descriptor | Hdac6 protein, Cyclopeptide des4.2.0, ZINC ION, ... (5 entities in total) |
| Functional Keywords | hydrolase, histone deacetylase, inhibitor, metallohydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Danio rerio (zebrafish) More |
| Total number of polymer chains | 4 |
| Total formula weight | 82888.42 |
| Authors | Watson, P.R.,Christianson, D.W. (deposition date: 2022-10-07, release date: 2023-04-19, Last modification date: 2023-11-15) |
| Primary citation | Watson, P.R.,Gupta, S.,Hosseinzadeh, P.,Brown, B.P.,Baker, D.,Christianson, D.W. Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6. Acs Chem.Biol., 18:959-968, 2023 Cited by PubMed: 37027789DOI: 10.1021/acschembio.3c00113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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