8EIS

Cryo-EM structure of octopus sensory receptor CRT1

Summary for 8EIS

• Entry DOI: 10.2210/pdb8eis/pdb
• EMDB information: 28163
• Descriptor: Octopus sensory receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol (3 entities in total)
• Functional Keywords: pentameric ligand gated ion channel, octopus sensory receptor, cys-loop receptor, structural protein
• Biological source: Octopus bimaculoides
• Total number of polymer chains: 5
• Total formula weight: 225847.96

Authors

Kang, G.,Kim, J.J.,Allard, C.A.H.,Valencia-Montoya, W.A.,Bellono, N.W.,Hibbs, R.E. (deposition date: 2022-09-15, release date: 2023-04-12, Last modification date: 2023-04-26)

• Primary citation: Kang, G.,Allard, C.A.H.,Valencia-Montoya, W.A.,van Giesen, L.,Kim, J.J.,Kilian, P.B.,Bai, X.,Bellono, N.W.,Hibbs, R.E.; Sensory specializations drive octopus and squid behaviour.; Nature, 616:378-383, 2023; PubMed: 37045917; DOI: 10.1038/s41586-023-05808-z

Experimental method

ELECTRON MICROSCOPY (2.62 Å)