8EE1
KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment AA5
Summary for 8EE1
Entry DOI | 10.2210/pdb8ee1/pdb |
Descriptor | 6-deoxyerythronolide B synthase, AA5 antibody heavy chain, AA5 antibody light chain, ... (4 entities in total) |
Functional Keywords | polyketide synthase, biosynthetic protein, transferase-immune system complex, transferase/immune system |
Biological source | Saccharopolyspora erythraea More |
Total number of polymer chains | 6 |
Total formula weight | 298347.92 |
Authors | Cogan, D.P.,Brodsky, K.L.,Guzman, K.M.,Mathews, I.I.,Khosla, C. (deposition date: 2022-09-06, release date: 2023-05-31, Last modification date: 2023-10-25) |
Primary citation | Guzman, K.M.,Cogan, D.P.,Brodsky, K.L.,Soohoo, A.M.,Li, X.,Sevillano, N.,Mathews, I.I.,Nguyen, K.P.,Craik, C.S.,Khosla, C. Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase. Biochemistry, 62:1589-1593, 2023 Cited by PubMed: 37184546DOI: 10.1021/acs.biochem.3c00156 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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