8ECM

Crystal Structure Analysis of Acetyl-CoA acetyltransferase from Firmicutes bacterium

This is a non-PDB format compatible entry.

Summary for 8ECM

• Entry DOI: 10.2210/pdb8ecm/pdb
• Descriptor: Acetyl-CoA acetyltransferase (2 entities in total)
• Functional Keywords: acetyl-coa acetyltransferase, transferase
• Biological source: Firmicutes bacterium
• Total number of polymer chains: 8
• Total formula weight: 359900.18

Authors

Seo, H.S.,Dhe-Paganon, S. (deposition date: 2022-09-02, release date: 2023-05-31, Last modification date: 2023-10-25)

• Primary citation: Mehta, R.S.,Mayers, J.R.,Zhang, Y.,Bhosle, A.,Glasser, N.R.,Nguyen, L.H.,Ma, W.,Bae, S.,Branck, T.,Song, K.,Sebastian, L.,Pacheco, J.A.,Seo, H.S.,Clish, C.,Dhe-Paganon, S.,Ananthakrishnan, A.N.,Franzosa, E.A.,Balskus, E.P.,Chan, A.T.,Huttenhower, C.; Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease.; Nat Med, 29:700-709, 2023; PubMed: 36823301; DOI: 10.1038/s41591-023-02217-7

Experimental method

X-RAY DIFFRACTION (1.89 Å)