8EC5

Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove

Summary for 8EC5

Entry DOI	10.2210/pdb8ec5/pdb
Descriptor	MHC class I antigen, Beta-2-microglobulin, peptide RARARARARARAFVKKKYCL, ... (4 entities in total)
Functional Keywords	mhc class i, antigen processing and presentation, long peptides, hla-b8, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	46051.13
Authors	Li, L.,Bouvier, M. (deposition date: 2022-09-01, release date: 2023-07-26, Last modification date: 2024-02-14)
Primary citation	Li, L.,Peng, X.,Batliwala, M.,Bouvier, M. Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing. Nat Commun, 14:5020-5020, 2023 Cited by PubMed: 37596268 DOI: 10.1038/s41467-023-40736-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.22 Å)

Structure validation