8E6J

3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)

Summary for 8E6J

• Entry DOI: 10.2210/pdb8e6j/pdb
• EMDB information: 27920
• Descriptor: Neuraminidase, 3H03 fragment antigen binding light chain, 3H03 fragment antigen binding heavy chain (3 entities in total)
• Functional Keywords: influenza, monoclonal antibody, na, h1n1, cross-reactive antibody, viral protein
• Biological source: Influenza A virus (A/Brevig Mission/1/1918(H1N1)); More
• Total number of polymer chains: 12
• Total formula weight: 390290.30

Authors

Turner, H.L.,Ozorowski, G.,Ward, A.B. (deposition date: 2022-08-22, release date: 2023-08-09, Last modification date: 2023-08-23)

• Primary citation: Hansen, L.,McMahon, M.,Turner, H.L.,Zhu, X.,Turner, J.S.,Ozorowski, G.,Stadlbauer, D.,Vahokoski, J.,Schmitz, A.J.,Rizk, A.A.,Alsoussi, W.B.,Strohmeier, S.,Yu, W.,Choreno-Parra, J.A.,Jimenez-Alvarez, L.,Cruz-Lagunas, A.,Zuniga, J.,Mudd, P.A.,Cox, R.J.,Wilson, I.A.,Ward, A.B.,Ellebedy, A.H.,Krammer, F.; Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.; Immunity, 56:1927-1938.e8, 2023; PubMed: 37506693; DOI: 10.1016/j.immuni.2023.07.004

Experimental method

ELECTRON MICROSCOPY (2.7 Å)