8E14

Cryo-EM structure of Rous sarcoma virus strand transfer complex

Summary for 8E14

• Entry DOI: 10.2210/pdb8e14/pdb
• EMDB information: 27823
• Descriptor: integrase, DNA (42-MER), DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*TP*AP*CP*TP*C)-3'), ... (5 entities in total)
• Functional Keywords: intasome, integrase-viral dna complex, strand transfer complex, viral protein-dna complex, viral protein/dna
• Biological source: Rous sarcoma virus - Prague C; More
• Total number of polymer chains: 14
• Total formula weight: 296713.36

Authors

Pandey, K.K.,Bera, S.,Shi, K.,Aihara, H.,Grandgenett, D.P. (deposition date: 2022-08-09, release date: 2023-04-26, Last modification date: 2023-10-18)

• Primary citation: Bera, S.,Shi, K.,Aihara, H.,Grandgenett, D.P.,Pandey, K.K.; Molecular determinants for Rous sarcoma virus intasome assemblies involved in retroviral integration.; J.Biol.Chem., 299:104730-104730, 2023; PubMed: 37084813; DOI: 10.1016/j.jbc.2023.104730

Experimental method

ELECTRON MICROSCOPY (3.36 Å)