8DGQ
Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide
Summary for 8DGQ
| Entry DOI | 10.2210/pdb8dgq/pdb |
| Descriptor | Ras GTPase-activating protein 1, Rho GTPase-activating protein 35, MALONATE ION, ... (4 entities in total) |
| Functional Keywords | sh2 domain, sh3 domain, phosphotyrosine, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 70344.11 |
| Authors | Stiegler, A.L.,Vish, K.J.,Boggon, T.J. (deposition date: 2022-06-24, release date: 2022-11-02, Last modification date: 2023-11-15) |
| Primary citation | Stiegler, A.L.,Vish, K.J.,Boggon, T.J. Tandem engagement of phosphotyrosines by the dual SH2 domains of p120RasGAP. Structure, 30:1603-1614.e5, 2022 Cited by PubMed: 36417908DOI: 10.1016/j.str.2022.10.009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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