8DG8

Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab

Summary for 8DG8

• Entry DOI: 10.2210/pdb8dg8/pdb
• EMDB information: 27418
• Descriptor: Fusion glycoprotein F0, 3x1 monoclonal antibody, VH region, 3x1 monoclonal antibody, VL region, ... (4 entities in total)
• Functional Keywords: cross-neutralizing, hpiv1, hpiv3, mab, immune system
• Biological source: Human parainfluenza 3 virus (strain NIH 47885); More
• Total number of polymer chains: 5
• Total formula weight: 192478.27

Authors

Rodarte, J.V.,Pancera, M. (deposition date: 2022-06-23, release date: 2023-02-22)

• Primary citation: Caban, M.,Rodarte, J.V.,Bibby, M.,Gray, M.D.,Taylor, J.J.,Pancera, M.,Boonyaratanakornkit, J.; Cross-protective antibodies against common endemic respiratory viruses.; Nat Commun, 14:798-798, 2023; PubMed: 36781872; DOI: 10.1038/s41467-023-36459-3

Experimental method

ELECTRON MICROSCOPY (3.62 Å)