8DF1

Chi3l1 bound by antibody C59

Summary for 8DF1

Entry DOI	10.2210/pdb8df1/pdb
Descriptor	Chitinase-3-like protein 1, C59 Fab Heavy chain, C59 Fab Light chain, ... (6 entities in total)
Functional Keywords	chi3l1, fab, immunotherapeutic, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	18
Total formula weight	524620.76
Authors	Wrapp, D.,McLellan, J.S. (deposition date: 2022-06-21, release date: 2023-03-01, Last modification date: 2023-10-25)
Primary citation	Li, L.,Wen, Y.,Wrapp, D.,Jeong, J.,Zhao, P.,Xiong, W.,Atkins, C.L.,Shan, Z.,Hui, D.,McLellan, J.S.,Zhang, N.,Ju, C.,An, Z. A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice. Antib Ther, 6:1-12, 2023 Cited by PubMed: 36683763 DOI: 10.1093/abt/tbac027 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation